Focused on the harm of staying up late to the body, this activity designed probiotics with the ability to eliminate reactive oxygen species, effectively alleviating the health damage caused by sleep loss. The students experienced life science, genetic engineering technology, plasmid extraction and other knowledge and skills in a comprehensive way, which also helped enhance students' interest in the field of biology.

Through this activity, the students had a glimpse of the current bio-genetic engineering, gene editing and other cutting-edge technologies, and carried out in-depth learning. Moreover, divided into different groups and under the guidance of the teacher, the students practiced a series of "operations in the biology book", such as transcription and expression, plasmid extraction, protein purification, etc., which enhanced the students’ understanding of the theories through experiments.

This activity expanded and deepened the knowledge on the biology test book and had a profound influence on students' future study and development.

√ Help students accumulate professional knowledge and develop their thinking skills in scientific research

√ Help students understand their future study direction and identify their major interests

√ Help students get to know excellent peers and accumulate initial resources

√ Offer the students deep lab experience and hands-on operation

iGEM (International Genetically Engineered Machine Competition), created by the Massachusetts Institute of Technology in 2003, It is a comprehensive international challenge that integrates life science, business, social science, computer, mathematics and other fields. Over the years, the iGEM Challenge has become a global STEM and business event with a wide range of participation and high profile.

In 2022, Hongrun Boyuan School won the Bronze Prize in the iGEM Challenge!